Hung Yi Kristal Kaan: search on Z-Library

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1

Macrocyclic α Helical Peptide Therapeutic Modality: A Perspective of Learnings and Challenges

Sawyer, Tomi K., Partridge, Anthony, Kaan, Hung Yi Kristal, Juang, Yu-Chi, Lim, Shuhui, Johannes, Charles, Yuen, Tsz Ying, Verma, Chandra, Kannan, Srinivasaraghavan, Aronica, Pietro, Sing, Tan Yaw, Sh

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

2

Structure−Activity Relationship and Multidrug Resistance Study of New S -trityl- l -Cysteine Derivatives As Inhibitors of Eg5

Kaan, Hung Yi Kristal, Weiss, Johanna, Menger, Dominik, Ulaganathan, Venkatasubramanian, Tkocz, Katarzyna, Laggner, Christian, Popowycz, Florence, Joseph, Benoît, Kozielski, Frank

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.43 MB

english, 2011

3

Structure and Plasticity of Endophilin and Sorting Nexin 9

Qi Wang, Hung Yi Kristal Kaan, Reshma Noordin Hooda, Shih Lin Goh, Holger Sondermann

Journal:

Year:

2008

Language:

english

File:

PDF, 2.69 MB

english, 2008

4

Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties

Partridge, Anthony W., Kaan, Hung Yi Kristal, Juang, Yu-Chi, Sadruddin, Ahmad, Lim, Shuhui, Brown, Christopher J., Ng, Simon, Thean, Dawn, Ferrer, Fernando, Johannes, Charles, Yuen, Tsz Ying, Kannan,

Journal:

Year:

2019

Language:

english

File:

PDF, 2.78 MB

english, 2019

5

Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles

Yuen, Tsz Ying, Brown, Christopher J., Xue, Yuezhen, Tan, Yaw Sing, Ferrer Gago, Fernando J., Lee, Xue Er, Neo, Jin Yong, Thean, Dawn, Kaan, Hung Yi Kristal, Partridge, Anthony W., Verma, Chandra S.,

Journal:

Chemical Science

Year:

2019

File:

PDF, 1.16 MB

2019

6

De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits

Ng, Simon, Juang, Yu-Chi, Chandramohan, Arun, Kaan, Hung Yi Kristal, Sadruddin, Ahmad, Yuen, Tsz Ying, Ferrer-Gago, Fernando J., Lee, XueâEr Cheryl, Liew, Xi, Johannes, Charles W., Brown, Christophe

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

File:

PDF, 2.26 MB

2020

7

Structural Basis for Inhibition of Eg5 by Dihydropyrimidines: Stereoselectivity of Antimitotic Inhibitors Enastron, Dimethylenastron and Fluorastrol

Kaan, Hung Yi Kristal, Ulaganathan, Venkatasubramanian, Rath, Oliver, Prokopcová, Hana, Dallinger, Doris, Kappe, C. Oliver, Kozielski, Frank

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 4.18 MB

english, 2010

8

Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles

Yuen, Tsz Ying, Brown, Christopher J., Xue, Yuezhen, Tan, Yaw Sing, Ferrer Gago, Fernando J., Lee, Xue Er, Neo, Jin Yong, Thean, Dawn, Kaan, Hung Yi Kristal, Partridge, Anthony W., Verma, Chandra S.,

Journal:

Chemical Science

Year:

2019

Language:

english

File:

PDF, 1.16 MB

english, 2019

9

Triphenylbutanamines: Kinesin Spindle Protein Inhibitors with in Vivo Antitumor Activity

Wang, Fang, Good, James A. D., Rath, Oliver, Kaan, Hung Yi Kristal, Sutcliffe, Oliver B., Mackay, Simon P., Kozielski, Frank

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.18 MB

english, 2012

10

An allosteric transition trapped in an intermediate state of a new kinesin–inhibitor complex

Kaan, Hung Yi Kristal, Ulaganathan, Venkatasubramanian, Hackney, David D., Kozielski, Frank

Journal:

Biochemical Journal

Year:

2010

Language:

english

File:

PDF, 790 KB

english, 2010

11

Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1

Wu, Donghui, Kaan, Hung Yi Kristal, Zheng, Xiaoxia, Tang, Xuhua, He, Yang, Vanessa Tan, Qianmin, Zhang, Neng, Song, Haiwei

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

12

Macrocyclization of an all- d linear Î±-helical peptide imparts cellular permeability

Kannan, Srinivasaraghavan, Aronica, Pietro G. A., Ng, Simon, Gek Lian, Dawn Thean, Frosi, Yuri, Chee, Sharon, Shimin, Jiang, Yuen, Tsz Ying, Sadruddin, Ahmad, Kaan, Hung Yi Kristal, Chandramohan, Arun

Journal:

Chemical Science

Year:

2020

File:

PDF, 1.46 MB

2020

13

Optimized S -Trityl- l -cysteine-Based Inhibitors of Kinesin Spindle Protein with Potent in Vivo Antitumor Activity in Lung Cancer Xenograft Models

Good, James A. D., Wang, Fang, Rath, Oliver, Kaan, Hung Yi Kristal, Talapatra, Sandeep K., Podgórski, Dawid, MacKay, Simon P., Kozielski, Frank

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 920 KB

english, 2013

14

Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex

Kaan, Hung Yi Kristal, Chan, Siew Wee, Tan, Siew Kim Joyce, Guo, Fusheng, Lim, Chun Jye, Hong, Wanjin, Song, Haiwei

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.13 MB

english, 2017

15

Structure–Activity Relationships and Molecular Docking of Novel Dihydropyrimidine-Based Mitotic Eg5 Inhibitors

Dr. Hana Prokopcová, Dr. Doris Dallinger, Prof. Dr. Georg Uray, Hung Yi Kristal Kaan, Dr. Venkatasubramanian Ulaganathan, Prof. Dr. Frank Kozielski, Dr. Christian Laggner, Prof. Dr. C. Oliver Kappe

Journal:

Year:

2010

Language:

english

File:

PDF, 455 KB

english, 2010

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